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| Digestion Archive for July 2000 |
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| 13 messages, last added Tue Nov 26 17:15:17 2002 |
[Date Index][Thread Index]
DIG-L: Bioreactor Inhibitory Data
Date: Mon, 10 Jul 2000 19:27:58 -0300
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The Crest Organization
We are a research group working on the development of a Bioreactor =
Dynamic Model in the UTN-Confluencia University, Neuquen, NW Patagonia, =
Argentina. Your e-m address was obtained from Internet.
Preliminar representations of the reactor included substrate & water =
pumping, temperature & acidity control and gas-expansion dynamics in =
combination with the Monod (Michaelis-Menten) monotonic function for the =
specific microbial growth rate (M) in terms of substrate concentration =
(S).
Now interested in incorporating substrate- and biomass-concentration (S =
& X) inhibitory effects on the anaerobic reaction, we are considering =
the application of the Haldane law M=3DS*Mmax/(Km+S+S**2/Ki). While =
bacteria death is accounted for by the Ki inhibition parameter applied =
to the quadratic term, the linear growth of the colonies is specified by =
the Michaelis-Menten constant determined by the enzyme-substrate =
combination used. Similarly, the Contoise law M=3DS*Mmax/(Kc*X+S) =
represents the biomass concentration inhibition through the Contoise =
constant Kc.
At this point of our work we are searching for any substantiated data =
(either measured or expected) for the (Km/Ki) ratio, the Kc constant and =
the typical biomass concentration applicable to an anaerobic reaction =
with mesophilic bacteria. Should you have available any feasible range =
for this inhibitory data, we would appreciate if you could forward it to =
the address below.
Ricardo A.Achilles
Member Bioreactor Project Group
UTN-Confluencia, Neuquen,ARG=20
achilles@ieee.org
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<!DOCTYPE HTML PUBLIC "-//W3C//DTD W3 HTML//EN">
The Crest Organization
We are a research group working on the development of a Bioreactor =
Dynamic=20 Model in the UTN-Confluencia University, Neuquen, NW Patagonia,
= Argentina. Your=20 e-m address was obtained from Internet.
Preliminar representations of the reactor included substrate & = water=20
pumping, temperature & acidity control and gas-expansion dynamics in =
combination with the Monod (Michaelis-Menten) monotonic function for the =
specific microbial growth rate (M) in terms of substrate concentration = (S).
Now interested in incorporating substrate- and biomass-concentration = (S
&=20 X) inhibitory effects on the anaerobic reaction, we are considering
the=20 application of the Haldane law M=3DS*Mmax/(Km+S+S**2/Ki). While
bacteria = death is=20 accounted for by the Ki inhibition parameter applied
to the quadratic = term, the=20 linear growth of the colonies is specified
by the Michaelis-Menten = constant=20 determined by the enzyme-substrate
combination used. Similarly, the = Contoise law=20 M=3DS*Mmax/(Kc*X+S)
represents the biomass concentration inhibition = through the=20 Contoise
constant Kc.
At this point of our work we are searching for any substantiated data =
(either=20 measured or expected) for the (Km/Ki) ratio, the Kc constant and
the = typical=20 biomass concentration applicable to an anaerobic reaction
with = mesophilic=20 bacteria. Should you have available any feasible range
for this = inhibitory data,=20 we would appreciate if you could forward it
to the address below.
Ricardo A.Achilles
Member Bioreactor Project Group
UTN-Confluencia, Neuquen,ARG
<3d.htm>achilles@ieee.<3d.htm>org
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